ITM3398
ITM3398
- Catalog: ITM3398
- Gene/Protein: CACNB3
- Product Description: Immunotag™ CACNB3 Polyclonal Antibody
$404.00
Price in reward points: 404
| Antibody Specification | |
| Datasheet | 
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| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | CACNB3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p |
| Recommended Dilution | WB: 1:500-1000 IHC: 1:200-500 |
| Concentration | 1 mg/ml |
| Reactive Species | Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthetic Peptide of CACNB3 |
| Specificity | The antibody detects endogenous CACNB3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Gene Name | CACNB3 |
| Accession No. | P54284 P54285 P54287 |
| Alternate Names | CACNB3; CACNLB3; Voltage-dependent L-type calcium channel subunit beta-3; CAB3; Calcium channel voltage-dependent subunit beta 3 |
| Description | calcium voltage-gated channel auxiliary subunit beta 3(CACNB3) Homo sapiens This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport. [provided by RefSeq, Oct 2011], |
| Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein,Cardiac muscle contraction,Hypertrophic cardiomyopathy (HCM),Arrhythmogenic right ventricular cardiomyopathy (ARVC),Dilated cardiomyopathy, |
| Protein Expression | Brain,Fetal brain, |
| Subcellular Localization | cytosol,plasma membrane,voltage-gated calcium channel complex,membrane,apical plasma membrane,L-type voltage-gated calcium channel complex, |
| Protein Function | function:The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.,similarity:Belongs to the calcium channel beta subunit family.,similarity:Contains 1 SH3 domain.,subunit:The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with CACNA2D4.,tissue specificity:Expressed mostly in brain, smooth muscle and ovary., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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