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DTT (1,4 Dithiothreitol) (5 Citations)



1,4 Dithiothreitol (DTT) is a small molecule reducing agent, also known as Cleland’s reagent. G-Biosciences DTT is a high quality proteomic grade DTT and is supplied in various sizes, including a OneQuant™ version. The OneQuant™ format features 40 vials of 7.7mg DTT for convenient one shot uses.


Dithiothreitol (DTT)

DTT is a common reducing agent used for the cleavage of disulfide bonds. Our DTT is supplied in bulk 5 gram quantities.

OneQuant™ DTT

OneQuant™ DTT are single aliquots that eliminate the need for weighing, preventing reagent loss and saving time. Simply add 90μL water to a single tube to generate a 0.5M DTT solution. Our OneQuant™ DTT is supplied with 40 individual tubes.

Features

  • Synonym: 1,4-dithiothreitol, threo-1,4-Dimercapto-2,3-butanediol, DL-Dithiothreitol, Cleland’s reagent, DTT, cleland′s reagent, dithiothreitol, 1,4-
  • CAS Number: 3483-12-3
  • Molecular Weight: 154.25
  • Linear Formula: HSCH2CH(OH)CH(OH)CH2SH

Applications

  • Reducing agent
  • Cleaves disulfide bonds
Protocol
786-077
Material Safety Data Sheet
786-077
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Technical Literature
Molecular Biology Handbook  A guide to our products for DNA and RNA.
Protein Cross-Linking Handbook  A detailed guide to protein cross-linkers and their reactions.
Protein Electrophoresis Handbook A guide to 1D and 2D protein electrophoresis products, including protein markers, electrophoresis buffers, 2D electrophoresis reagents, clean-up reagents and stains. The guide also offers protein sample preparation products.
Western Blotting Handbook From protein electrophoresis and Western transfer to blocking, probing and detection of membrane immobilized proteins.

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